Instrumentation
Platforms & facilities
The Fernández Lab designs, operates, and pushes the limits of a broad portfolio of mass spectrometry platforms spanning triple quadrupoles, ion mobility, ultrahigh-resolution FT-ICR and Orbitrap, and MALDI imaging, many of them configured with custom ion sources. Dr. Fernández is the faculty advisor to Georgia Tech's IBB Systems Mass Spectrometry Core (SyMS-C), a shared facility serving researchers across campus.
Waters Xevo Triple Quadrupole
Tandem-quadrupole LC-MS/MS, equipped with DESI and ESI sources.
Waters SELECT SERIES Cyclic IMS
High-resolution cyclic ion mobility Q-ToF, equipped with DESI and ESI sources.
Waters SELECT SERIES MRT
Multi-reflecting time-of-flight MS for very high mass resolving power, equipped with DESI and ESI sources.
Waters Synapt G2-S HDMS
Traveling-wave ion mobility Q-ToF with an online Acquity UPLC and dual-polarity lock-spray ESI source.
Bruker solariX 12 T FT-ICR
12-Tesla Fourier-transform ion cyclotron resonance MS with direct-infusion ESI and MALDI sources.
Thermo Q Exactive Plus Orbitrap
High-resolution Orbitrap MS configured with ESI, triboelectric nanogenerator (TENG), and laser ionization sources.
Thermo Orbitrap ID-X Tribrid
Tribrid mass spectrometer pairing a quadrupole, Orbitrap, and linear ion trap for high-resolution multi-stage (MSn) analysis and small-molecule structural identification.
Thermo Orbitrap IQ-X Tribrid
Tribrid Orbitrap mass spectrometer for ultrahigh-resolution MSn and structural elucidation, coupled to a Thermo UltiMate 3000 LC.
Thermo Orbitrap Exploris 240 (×2 units)
High-resolution Orbitrap LC-MS platform for quantitative and discovery metabolomics and proteomics. Two systems in operation.
Bruker rapifleX MALDI-ToF
High-speed MALDI time-of-flight MS for mass spectrometry imaging.
HTX TM-Sprayer
Automated matrix sprayer for reproducible MALDI imaging sample preparation.
HTX subliMATE
Automated vacuum sublimation system for solvent-free MALDI matrix deposition in mass spectrometry imaging.
IonSense DART Source
Direct Analysis in Real Time (DART) ambient ionization source for rapid, open-air sampling.
Waters TQ-S Micro
Compact tandem-quadrupole LC-MS/MS for targeted quantitation.
Shared facility
IBB Systems Mass Spectrometry Core (SyMS-C)
Faculty Advisor (2015–present)
A Georgia Tech shared facility providing mass spectrometry services and expertise to the campus research community, housed in the Petit Institute for Bioengineering & Bioscience.